Illicit drug use in Reykjavik by wastewater-based epidemiology

Estimation of illicit drug use on a community level by wastewater-based epidemiology (WBE) is both an objective and reliable way to establish near real-time results. Wastewater samples were collected at eleven timepoints in Reykjavik from 2017 2020. The commonly abused drugs Iceland (amphetamine, methamphetamine, 3,4-methylenedioxymethamphetamine (MDMA), cocaine, cannabis) was estimated. Solid phase extraction ultra-high performance liquid chromatography coupled tandem mass spectrometry used for analysis. Estimated amphetamine methamphetamine showed signs increase 2020 with being the dominant stimulant market. MDMA remained stable Results large cocaine 2019 but interestingly, marked decrease during COVID-19 pandemic. Cannabis pandemic WBE corresponded data based two other indicators use, seizure driving under influence cases. Both temporal spatial trends successfully estimated using WBE, complimenting which provided comprehensive picture abuse Reykjavik.